| Protein dynamism and evolvability N Tokuriki, DS Tawfik Science 324 (5924), 203-207, 2009 | 1001 | 2009 |
| Stability effects of mutations and protein evolvability N Tokuriki, DS Tawfik Current opinion in structural biology 19 (5), 596-604, 2009 | 969 | 2009 |
| How protein stability and new functions trade off N Tokuriki, F Stricher, L Serrano, DS Tawfik PLoS computational biology 4 (2), e1000002, 2008 | 622 | 2008 |
| Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein S Bershtein, M Segal, R Bekerman, N Tokuriki, DS Tawfik Nature 444 (7121), 929-932, 2006 | 476 | 2006 |
| The stability effects of protein mutations appear to be universally distributed N Tokuriki, F Stricher, J Schymkowitz, L Serrano, DS Tawfik Journal of molecular biology 369 (5), 1318-1332, 2007 | 454 | 2007 |
| Chaperonin overexpression promotes genetic variation and enzyme evolution N Tokuriki, DS Tawfik Nature 459 (7247), 668-673, 2009 | 397 | 2009 |
| The role of protein dynamics in the evolution of new enzyme function E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ... Nature chemical biology 12 (11), 944-950, 2016 | 307 | 2016 |
| What makes an enzyme promiscuous? A Babtie, N Tokuriki, F Hollfelder Current opinion in chemical biology 14 (2), 200-207, 2010 | 263 | 2010 |
| Do viral proteins possess unique biophysical features? N Tokuriki, CJ Oldfield, VN Uversky, IN Berezovsky, DS Tawfik Trends in biochemical sciences 34 (2), 53-59, 2009 | 256 | 2009 |
| Protein folding by the effects of macromolecular crowding N Tokuriki, M Kinjo, S Negi, M Hoshino, Y Goto, I Urabe, T Yomo Protein Science 13 (1), 125-133, 2004 | 254 | 2004 |
| Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme N Tokuriki, CJ Jackson, L Afriat-Jurnou, KT Wyganowski, R Tang, ... Nature Communications 3 (1), 1257, 2012 | 248 | 2012 |
| How mutational epistasis impairs predictability in protein evolution and design CM Miton, N Tokuriki Protein Science 25 (7), 1260-1272, 2016 | 203 | 2016 |
| Noise–mean relationship in mutated promoters G Hornung, R Bar-Ziv, D Rosin, N Tokuriki, DS Tawfik, M Oren, N Barkai Genome research 22 (12), 2409-2417, 2012 | 184 | 2012 |
| Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily E Akiva, JN Copp, N Tokuriki, PC Babbitt Proceedings of the National Academy of Sciences 114 (45), E9549-E9558, 2017 | 143 | 2017 |
| Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase CJ Jackson, JL Foo, N Tokuriki, L Afriat, PD Carr, HK Kim, G Schenk, ... Proceedings of the National Academy of Sciences 106 (51), 21631-21636, 2009 | 142 | 2009 |
| Connectivity between catalytic landscapes of the metallo-β-lactamase superfamily F Baier, N Tokuriki Journal of Molecular Biology 426 (13), 2442-2456, 2014 | 127 | 2014 |
| Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein BE Clifton, JA Kaczmarski, PD Carr, ML Gerth, N Tokuriki, CJ Jackson Nature chemical biology 14 (6), 542-547, 2018 | 107 | 2018 |
| Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme G Yang, DW Anderson, F Baier, E Dohmen, N Hong, PD Carr, ... Nature Chemical Biology 15 (11), 1120-1128, 2019 | 106 | 2019 |
| Modulating protein stability–directed evolution strategies for improved protein function RD Socha, N Tokuriki The FEBS journal 280 (22), 5582-5595, 2013 | 101 | 2013 |
| Laboratory evolution of protein conformational dynamics EC Campbell, GJ Correy, PD Mabbitt, AM Buckle, N Tokuriki, CJ Jackson Current Opinion in Structural Biology 50, 49-57, 2018 | 99 | 2018 |
Colin JacksonProfessor, Research School of Chemistry, Australian National UniversityVerified email at anu.edu.au
