| Natural products in drug discovery: advances and opportunities AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran Nature reviews Drug discovery 20 (3), 200-216, 2021 | 3681 | 2021 |
| Carbonic anhydrases: novel therapeutic applications for inhibitors and activators CT Supuran Nature reviews Drug discovery 7 (2), 168-181, 2008 | 3563 | 2008 |
| Interfering with pH regulation in tumours as a therapeutic strategy D Neri, CT Supuran Nature reviews Drug discovery 10 (10), 767-777, 2011 | 1691 | 2011 |
| Carbonic anhydrase inhibitors CT Supuran, A Scozzafava, A Casini Medicinal research reviews 23 (2), 146-189, 2003 | 1539 | 2003 |
| Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms? V Alterio, A Di Fiore, K D’Ambrosio, CT Supuran, G De Simone Chemical reviews 112 (8), 4421-4468, 2012 | 1285 | 2012 |
| Structure and function of carbonic anhydrases CT Supuran Biochemical Journal 473 (14), 2023-2032, 2016 | 882 | 2016 |
| Anticancer and antiviral sulfonamides A Scozzafava, T Owa, A Mastrolorenzo, CT Supuran Current medicinal chemistry 10 (11), 925-953, 2003 | 881 | 2003 |
| Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 791 | 2011 |
| How many carbonic anhydrase inhibition mechanisms exist? CT Supuran Journal of enzyme inhibition and medicinal chemistry 31 (3), 345-360, 2016 | 779 | 2016 |
| Carbonic anhydrase inhibitors CT Supuran Bioorganic & medicinal chemistry letters 20 (12), 3467-3474, 2010 | 738 | 2010 |
| Carbonic anhydrases as targets for medicinal chemistry CT Supuran, A Scozzafava Bioorganic & medicinal chemistry 15 (13), 4336-4350, 2007 | 737 | 2007 |
| Carbonic anhydrase inhibitors and their therapeutic potential CT Supuran, A Scozzafava Expert Opinion on Therapeutic Patents 10 (5), 575-600, 2000 | 695 | 2000 |
| Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH E Švastová, A Hulı́ková, M Rafajová, M Zat'ovičová, A Gibadulinová, ... FEBS letters 3 (577), 439-445, 2004 | 683 | 2004 |
| Structure-based drug discovery of carbonic anhydrase inhibitors CT Supuran Journal of enzyme inhibition and medicinal chemistry 27 (6), 759-772, 2012 | 653 | 2012 |
| Carbonic anhydrases-an overview CT Supuran Current pharmaceutical design 14 (7), 603-614, 2008 | 610 | 2008 |
| Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents CT Supuran, A Casini, A Scozzafava Medicinal Research Reviews 23 (5), 535-558, 2003 | 581 | 2003 |
| Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX V Alterio, M Hilvo, A Di Fiore, CT Supuran, P Pan, S Parkkila, A Scaloni, ... Proceedings of the National Academy of Sciences 106 (38), 16233-16238, 2009 | 577 | 2009 |
| Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors A Maresca, C Temperini, H Vu, NB Pham, SA Poulsen, A Scozzafava, ... Journal of the American Chemical Society 131 (8), 3057-3062, 2009 | 570 | 2009 |
| Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition A Weber, A Casini, A Heine, D Kuhn, CT Supuran, A Scozzafava, G Klebe Journal of medicinal chemistry 47 (3), 550-557, 2004 | 552 | 2004 |
| Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis F Pacchiano, F Carta, PC McDonald, Y Lou, D Vullo, A Scozzafava, ... Journal of medicinal chemistry 54 (6), 1896-1902, 2011 | 535 | 2011 |
Andrea ScozzafavaProfessore di chimica, Università di FirenzeVerified email at unifi.it
