| Metabolomic strategies for the identification of new enzyme functions and metabolic pathways GA Prosser, G Larrouy‐Maumus, LPS de Carvalho EMBO reports 15 (6), 657-669, 2014 | 143 | 2014 |
| Kinetic mechanism and inhibition of Mycobacterium tuberculosis d‐alanine:d‐alanine ligase by the antibiotic d‐cycloserine GA Prosser, LPS de Carvalho The FEBS journal 280 (4), 1150-1166, 2013 | 137 | 2013 |
| Discovery and evaluation of Escherichia coli nitroreductases that activate the anti-cancer prodrug CB1954 GA Prosser, JN Copp, SP Syddall, EM Williams, JB Smaill, WR Wilson, ... Biochemical pharmacology 79 (5), 678-687, 2010 | 137 | 2010 |
| Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis GA Prosser, LPS de Carvalho ACS medicinal chemistry letters 4 (12), 1233-1237, 2013 | 120 | 2013 |
| The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition G Prosser, J Brandenburg, N Reiling, CE Barry III, RJ Wilkinson, ... Microbes and infection 19 (3), 177-192, 2017 | 82 | 2017 |
| 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action … D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ... ACS infectious diseases 4 (6), 954-969, 2018 | 72 | 2018 |
| Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A GA Prosser, JN Copp, AM Mowday, CP Guise, SP Syddall, EM Williams, ... Biochemical pharmacology 85 (8), 1091-1103, 2013 | 62 | 2013 |
| Reinterpreting the Mechanism of Inhibition of Mycobacterium tuberculosis d-Alanine:d-Alanine Ligase by d-Cycloserine GA Prosser, LPS de Carvalho Biochemistry 52 (40), 7145-7149, 2013 | 57 | 2013 |
| Role of post‐translational modifications in the acquisition of drug resistance in Mycobacterium tuberculosis G Arora, A Bothra, G Prosser, K Arora, A Sajid The FEBS Journal 288 (11), 3375-3393, 2021 | 56 | 2021 |
| Metabolomics of Mycobacterium tuberculosis M Nandakumar, GA Prosser, LPS de Carvalho, K Rhee Mycobacteria Protocols, 105-115, 2015 | 48 | 2015 |
| Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis GA Prosser, A Rodenburg, H Khoury, C de Chiara, S Howell, AP Snijders, ... Antimicrobial agents and chemotherapy 60 (10), 6091-6099, 2016 | 46 | 2016 |
| d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition C de Chiara, M Homšak, GA Prosser, HL Douglas, A Garza-Garcia, ... Nature chemical biology 16 (6), 686-694, 2020 | 44 | 2020 |
| Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes D Evangelopoulos, GA Prosser, A Rodgers, BM Dagg, B Khatri, MM Ho, ... Nature communications 10 (1), 4177, 2019 | 44 | 2019 |
| uvrB gene deletion enhances SOS chromotest sensitivity for nitroreductases that preferentially generate the 4-hydroxylamine metabolite of the anti-cancer prodrug CB1954 GA Prosser, AV Patterson, DF Ackerley Journal of biotechnology 150 (1), 190-194, 2010 | 25 | 2010 |
| Development and Optimization of Chromosomally-Integrated Fluorescent Mycobacterium tuberculosis Reporter Constructs K Kolbe, AC Bell, GA Prosser, M Assmann, HJ Yang, HE Forbes, ... Frontiers in microbiology 11, 591866, 2020 | 20 | 2020 |
| Restoring tumour selectivity of the bioreductive prodrug PR-104 by developing an analogue resistant to aerobic metabolism by human aldo-keto reductase 1C3 MR Abbattista, A Ashoorzadeh, CP Guise, AM Mowday, R Mittra, S Silva, ... Pharmaceuticals 14 (12), 1231, 2021 | 6 | 2021 |
| A gain-of-function positive-selection expression plasmid that enables high-efficiency cloning GA Prosser, EM Williams, JA Sissons, KE Walmsley, MR Parker, ... Biotechnology letters 37, 383-389, 2015 | 6 | 2015 |
| GlnA3Mt is able to glutamylate spermine but it is not essential for the detoxification of spermine in Mycobacterium tuberculosis S Krysenko, CS Emani, M Bäuerle, M Oswald, A Kulik, C Meyners, ... Journal of Bacteriology, e00439-24, 2025 | 4 | 2025 |
| Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis C de Chiara, GA Prosser, R Ogrodowicz, LPS de Carvalho ACS bio & med Chem Au 3 (3), 233-239, 2023 | 3 | 2023 |
| Antibiotic resistance evasion is explained by rare mutation frequency and not by lack of compensatory mechanisms D Evangelopoulos, GA Prosser, A Rodgers, BM Dagg, B Khatri, MM Ho, ... BioRxiv, 374215, 2018 | 2 | 2018 |
