| Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation ME Figueroa, O Abdel-Wahab, C Lu, PS Ward, J Patel, A Shih, Y Li, ... Cancer cell 18 (6), 553-567, 2010 | 3165 | 2010 |
| Prognostic relevance of integrated genetic profiling in acute myeloid leukemia JP Patel, M Gönen, ME Figueroa, H Fernandez, Z Sun, J Racevskis, ... New England Journal of Medicine 366 (12), 1079-1089, 2012 | 2406 | 2012 |
| IDH mutation impairs histone demethylation and results in a block to cell differentiation C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ... Nature 483 (7390), 474-478, 2012 | 2216 | 2012 |
| methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ... Genome biology 13, 1-9, 2012 | 1922 | 2012 |
| Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ... Cancer cell 20 (1), 11-24, 2011 | 1502 | 2011 |
| Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ... Nature biotechnology 28 (8), 848-855, 2010 | 1423 | 2010 |
| Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia A Melnick, JD Licht Blood, The Journal of the American Society of Hematology 93 (10), 3167-3215, 1999 | 1387 | 1999 |
| The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ... Nature medicine 23 (11), 1369-1376, 2017 | 1104 | 2017 |
| A molecular roadmap of reprogramming somatic cells into iPS cells JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ... Cell 151 (7), 1617-1632, 2012 | 1015 | 2012 |
| DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia ME Figueroa, S Lugthart, Y Li, C Erpelinck-Verschueren, X Deng, ... Cancer cell 17 (1), 13-27, 2010 | 1000 | 2010 |
| The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ... Science 364 (6436), eaau8650, 2019 | 978 | 2019 |
| EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ... Cancer cell 23 (5), 677-692, 2013 | 952 | 2013 |
| The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee E Campo, ES Jaffe, JR Cook, L Quintanilla-Martinez, SH Swerdlow, ... Blood, The Journal of the American Society of Hematology 140 (11), 1229-1253, 2022 | 940 | 2022 |
| Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis L Busque, JP Patel, ME Figueroa, A Vasanthakumar, S Provost, ... Nature genetics 44 (11), 1179-1181, 2012 | 914 | 2012 |
| ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ... Cancer cell 22 (2), 180-193, 2012 | 709 | 2012 |
| IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ... Nature 488 (7413), 656-659, 2012 | 621 | 2012 |
| DNMT1-interacting RNAs block gene-specific DNA methylation A Di Ruscio, AK Ebralidze, T Benoukraf, G Amabile, LA Goff, J Terragni, ... Nature 503 (7476), 371-376, 2013 | 600 | 2013 |
| Comparative isoschizomer profiling of cytosine methylation: the HELP assay B Khulan, RF Thompson, K Ye, MJ Fazzari, M Suzuki, E Stasiek, ... Genome research 16 (8), 1046-1055, 2006 | 479 | 2006 |
| The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 452 | 2015 |
| Outcome of deferred initial therapy in mantle-cell lymphoma P Martin, A Chadburn, P Christos, K Weil, RR Furman, J Ruan, R Elstrom, ... Journal of clinical oncology 27 (8), 1209-1213, 2009 | 447 | 2009 |
Maria E. FigueroaProfessor in Biochemistry & Molecular Biology, Sylvester Comprehensive Cancer Center, University ofVerified email at miami.edu
