Connectivity between catalytic landscapes of the metallo-β-lactamase superfamily F Baier, N Tokuriki Journal of Molecular Biology 426 (13), 2442-2456, 2014 | 127 | 2014 |
Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme G Yang, DW Anderson, F Baier, E Dohmen, N Hong, PD Carr, ... Nature Chemical Biology 15 (11), 1120-1128, 2019 | 107 | 2019 |
Evolution of enzyme superfamilies: comprehensive exploration of sequence–function relationships F Baier, JN Copp, N Tokuriki Biochemistry 55 (46), 6375-6388, 2016 | 84 | 2016 |
Oil formation from glucose with formic acid and cobalt catalyst in hot-compressed water M Watanabe, F Bayer, A Kruse Carbohydrate research 341 (18), 2891-2900, 2006 | 70 | 2006 |
Distinct metal isoforms underlie promiscuous activity profiles of metalloenzymes F Baier, J Chen, M Solomonson, NCJ Strynadka, N Tokuriki ACS chemical biology 10 (7), 1684-1693, 2015 | 53 | 2015 |
Conformational tinkering drives evolution of a promiscuous activity through indirect mutational effects G Yang, N Hong, F Baier, CJ Jackson, N Tokuriki Biochemistry 55 (32), 4583-4593, 2016 | 51 | 2016 |
Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes F Baier, N Hong, G Yang, A Pabis, CM Miton, A Barrozo, PD Carr, ... Elife 8, e40789, 2019 | 47 | 2019 |
Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase M Purg, A Pabis, F Baier, N Tokuriki, C Jackson, SCL Kamerlin Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016 | 35 | 2016 |
The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis DW Anderson, F Baier, G Yang, N Tokuriki Nature Communications 12 (1), 3867, 2021 | 31 | 2021 |
Environment-dependent epistasis increases phenotypic diversity in gene regulatory networks F Baier, F Gauye, R Perez-Carrasco, JL Payne, Y Schaerli Science Advances 9 (21), eadf1773, 2023 | 19 | 2023 |
Secondary environmental variation creates a shifting evolutionary watershed for the methyl-parathion hydrolase enzyme DW Anderson, F Baier, G Yang, N Tokuriki Biorxiv, 833764, 2019 | 4 | 2019 |
A direct experimental test of Ohno’s hypothesis L Mihajlovic, BR Iyengar, F Baier, I Barbier, J Iwaszkiewicz, V Zoete, ... bioRxiv, 2023.09. 25.559237, 2023 | 3 | 2023 |
Addressing evolutionary questions with synthetic biology F Baier, Y Schaerli Evolutionary systems biology: advances, questions, and opportunities, 135-157, 2021 | 3 | 2021 |
Diversity and biogeography of the bacterial microbiome in glacier-fed streams L Ezzat, H Peter, M Bourquin, SB Busi, G Michoud, S Fodelianakis, ... Nature, 1-9, 2025 | 2 | 2025 |
Higher-order epistatic networks underlie the evolutionary fitness landscape of a xenobiotic-degrading enzyme G Yang, DW Anderson, F Baier, E Dohmen, N Hong, PD Carr, ... bioRxiv, 504811, 2018 | 2 | 2018 |
CHARACTERIZING THE RESILIENCE AND ADAPTATION OF BIOFILM COMMUNITIES TO CLIMATE CHANGE IN GLACIER-FED STREAMS M Gonzalez Mateu, D Touchette, HM Peter, F Baier, G Michoud, N Deluigi, ... ASLO Aquatic Science Meeting, 2023 | | 2023 |
Data from: Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes F Baier, N Hong, G Yang, A Pabis, CM Miton, A Barrozo, PD Carr, ... Borealis, 2021 | | 2021 |
Author Correction: Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme G Yang, DW Anderson, F Baier, E Dohmen, N Hong, PD Carr, ... Nature chemical biology 16 (8), 930, 2020 | | 2020 |
The evolution of enzyme functions in the metallo-β-lactamase superfamily F Baier University of British Columbia, 2017 | | 2017 |
SBER A Bagnoud, F Baier, TI Battin, M Bekliz, M Boix Canadell, M Bourquin, ... | | |