One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution A Zinchenko, SRA Devenish, B Kintses, PY Colin, M Fischlechner, ... Analytical chemistry 86 (5), 2526-2533, 2014 | 258 | 2014 |
Enzyme engineering in biomimetic compartments PY Colin, A Zinchenko, F Hollfelder Current opinion in structural biology 33, 42-51, 2015 | 63 | 2015 |
Investigating host-microbiome interactions by droplet based microfluidics AS Tauzin, MR Pereira, LD Van Vliet, PY Colin, E Laville, J Esque, ... Microbiome 8, 1-20, 2020 | 49 | 2020 |
Ultrahigh-throughput directed evolution of a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase JD Schnettler, OJ Klein, TS Kaminski, PY Colin, F Hollfelder Journal of the American Chemical Society 145 (2), 1083-1096, 2022 | 28 | 2022 |
Ultrahigh-Throughput Screening of Single-Cell Lysates for Directed Evolution and Functional Metagenomics F Gielen, PY Colin, P Mair, F Hollfelder Methods in Molecular Biology 1685, 297-309, 2017 | 20 | 2017 |
Bioinspired genotype–phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins LD van Vliet, PY Colin, F Hollfelder Interface Focus 5 (4), 20150035, 2015 | 17 | 2015 |
Engineering improved ethylene production: Leveraging systems biology and adaptive laboratory evolution S Vaud, N Pearcy, M Hanževački, AMW Van Hagen, S Abdelrazig, L Safo, ... Metabolic Engineering 67, 308-320, 2021 | 12 | 2021 |
Functional and computational identification of a rescue mutation near the active site of an mRNA methyltransferase PY Colin, PA Dalby Scientific Reports 10 (1), 21841, 2020 | 4 | 2020 |
Ultrahigh-throughput directed evolution of a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase D Schnettler Fernández, OJ Klein, TS Kaminski, PY Colin, F Hollfelder bioRxiv, 2022.02. 14.480337, 2022 | 1 | 2022 |
Ultrahigh-throughput directed evolution of a metal-free α/β-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase OJ Klein, TS Kaminski, P Colin, F Hollfelder | | 2022 |
A new ultra-high throughput screening technique detects human glycans degradation pathways in IBD AS Tauzin, MR Pereira, LD Van Vliet, PY Colin, E Laville, J Esque, ... | | 2020 |
Engineering 2’O-mRNA methyltransferases for industrial biocatalysis PY Colin, PA Dalby, M Stahley, J Davis | | 2017 |