Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway C Deisenroth, Y Zhang Oncogene 29 (30), 4253-4260, 2010 | 356 | 2010 |
The next generation blueprint of computational toxicology at the US Environmental Protection Agency RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ... Toxicological Sciences 169 (2), 317-332, 2019 | 286 | 2019 |
An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction E Macias, A Jin, C Deisenroth, K Bhat, H Mao, MS Lindström, Y Zhang Cancer cell 18 (3), 231-243, 2010 | 227 | 2010 |
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation MS Lindstroöm, A Jin, C Deisenroth, GW Wolf, Y Zhang Molecular and cellular biology, 2007 | 174 | 2007 |
RP–MDM2–p53 pathway: Linking ribosomal biogenesis and tumor surveillance Y Liu, C Deisenroth, Y Zhang Trends in cancer 2 (4), 191-204, 2016 | 110 | 2016 |
Putting a finger on growth surveillance: insight into MDM2 zinc finger-ribosomal protein interactions MS Lindstrom, C Deisenroth, Y Zhang Cell cycle 6 (4), 434-437, 2007 | 79 | 2007 |
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation C Deisenroth, Y Itahana, L Tollini, A Jin, Y Zhang Journal of Biological Chemistry 286 (32), 28343-28356, 2011 | 77 | 2011 |
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53 C Deisenroth, AR Thorner, T Enomoto, CM Perou, Y Zhang Molecular and cellular biology, 2010 | 75 | 2010 |
The evolution of the ribosomal protein–MDM2–p53 pathway C Deisenroth, DA Franklin, Y Zhang Cold Spring Harbor perspectives in medicine 6 (12), a026138, 2016 | 71 | 2016 |
The ribosomal protein-Mdm2-p53 pathway and energy metabolism: bridging the gap between feast and famine C Deisenroth, Y Zhang Genes & cancer 2 (4), 392-403, 2011 | 68 | 2011 |
Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay AR Buckalew, J Wang, AS Murr, C Deisenroth, WM Stewart, TE Stoker, ... Archives of toxicology 94 (3), 873-885, 2020 | 45 | 2020 |
Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis B Foley, DL Doheny, MB Black, SN Pendse, BA Wetmore, RA Clewell, ... Toxicological Sciences 155 (1), 85-100, 2017 | 37 | 2017 |
MYC is an early response regulator of human adipogenesis in adipose stem cells C Deisenroth, MB Black, S Pendse, L Pluta, SM Witherspoon, ... PLoS One 9 (12), e114133, 2014 | 35 | 2014 |
Evaluation of androgen assay results using a curated Hershberger database NC Kleinstreuer, P Browne, X Chang, R Judson, W Casey, P Ceger, ... Reproductive Toxicology 81, 272-280, 2018 | 32 | 2018 |
Development of a curated Hershberger database P Browne, NC Kleinstreuer, P Ceger, C Deisenroth, N Baker, K Markey, ... Reproductive Toxicology 81, 259-271, 2018 | 30 | 2018 |
Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation V Soldatow, RC Peffer, OJ Trask, DE Cowie, ME Andersen, E LeCluyse, ... Toxicology in Vitro 36, 224-237, 2016 | 29 | 2016 |
Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening C Deisenroth, VY Soldatow, J Ford, W Stewart, C Brinkman, EL LeCluyse, ... Toxicological Sciences 174 (1), 63-78, 2020 | 26 | 2020 |
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods PD McMullen, S Bhattacharya, CG Woods, SN Pendse, MT McBride, ... Toxicology in Vitro 64, 104463, 2020 | 25 | 2020 |
The alginate immobilization of metabolic enzymes platform retrofits an estrogen receptor transactivation assay with metabolic competence C Deisenroth, DE DeGroot, T Zurlinden, A Eicher, J McCord, MY Lee, ... Toxicological Sciences 178 (2), 281-301, 2020 | 24 | 2020 |
Protection of cell therapeutics from antibody-mediated killing by CD64 overexpression A Gravina, G Tediashvili, R Rajalingam, Z Quandt, C Deisenroth, ... Nature biotechnology 41 (5), 717-727, 2023 | 22 | 2023 |