C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ... Science 353 (6299), aaf5573, 2016 | 2339 | 2016 |
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems S Shmakov, OO Abudayyeh, KS Makarova, YI Wolf, JS Gootenberg, ... Molecular cell 60 (3), 385-397, 2015 | 1462 | 2015 |
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ... Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011 | 1060 | 2011 |
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 752 | 2012 |
Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system KA Datsenko, K Pougach, A Tikhonov, BL Wanner, K Severinov, ... Nature communications 3 (1), 945, 2012 | 713 | 2012 |
Transcription, processing and function of CRISPR cassettes in Escherichia coli K Pougach, E Semenova, E Bogdanova, KA Datsenko, M Djordjevic, ... Molecular microbiology 77 (6), 1367-1379, 2010 | 333 | 2010 |
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ... PLoS genetics 9 (9), e1003742, 2013 | 290 | 2013 |
Genome-Wide Identification of Regulatory RNAs in the Human Pathogen Clostridium difficile OA Soutourina, M Monot, P Boudry, L Saujet, C Pichon, O Sismeiro, ... PLoS genetics 9 (5), e1003493, 2013 | 283 | 2013 |
Low‐molecular‐weight post‐translationally modified microcins K Severinov, E Semenova, A Kazakov, T Kazakov, MS Gelfand Molecular microbiology 65 (6), 1380-1394, 2007 | 170 | 2007 |
High-throughput analysis of type IE CRISPR/Cas spacer acquisition in E. coli E Savitskaya, E Semenova, V Dedkov, A Metlitskaya, K Severinov RNA biology 10 (5), 716-725, 2013 | 135 | 2013 |
Foreign DNA acquisition by the IF CRISPR–Cas system requires all components of the interference machinery D Vorontsova, KA Datsenko, S Medvedeva, J Bondy-Denomy, ... Nucleic acids research 43 (22), 10848-10860, 2015 | 104 | 2015 |
Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type IE CRISPR-Cas interfering complex E Semenova, E Savitskaya, O Musharova, A Strotskaya, D Vorontsova, ... Proceedings of the National Academy of Sciences 113 (27), 7626-7631, 2016 | 103 | 2016 |
Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3′-terminal segment of guide RNA V Mekler, L Minakhin, E Semenova, K Kuznedelov, K Severinov Nucleic acids research 44 (6), 2837-2845, 2016 | 103 | 2016 |
Analysis of CRISPR system function in plant pathogen Xanthomonas oryzae E Semenova, M Nagornykh, M Pyatnitskiy, II Artamonova, K Severinov FEMS microbiology letters 296 (1), 110-116, 2009 | 102 | 2009 |
The antibacterial threaded-lasso peptide capistruin inhibits bacterial RNA polymerase K Kuznedelov, E Semenova, TA Knappe, D Mukhamedyarov, ... Journal of molecular biology 412 (5), 842-848, 2011 | 101 | 2011 |
Analysis of Promoter Targets for Escherichia coli Transcription Elongation Factor GreA In Vivo and In Vitro E Stepanova, J Lee, M Ozerova, E Semenova, K Datsenko, BL Wanner, ... Journal of bacteriology 189 (24), 8772-8785, 2007 | 95 | 2007 |
The action of Escherichia coli CRISPR–Cas system on lytic bacteriophages with different lifestyles and development strategies A Strotskaya, E Savitskaya, A Metlitskaya, N Morozova, KA Datsenko, ... Nucleic acids research 45 (4), 1946-1957, 2017 | 90 | 2017 |
Pervasive generation of oppositely oriented spacers during CRISPR adaptation S Shmakov, E Savitskaya, E Semenova, MD Logacheva, KA Datsenko, ... Nucleic acids research 42 (9), 5907-5916, 2014 | 85 | 2014 |
Function of the CRISPR-Cas system of the human pathogen Clostridium difficile P Boudry, E Semenova, M Monot, KA Datsenko, A Lopatina, O Sekulovic, ... MBio 6 (5), 10.1128/mbio. 01112-15, 2015 | 78 | 2015 |
Control of bacterial motility by environmental factors in polarly flagellated and peritrichous bacteria isolated from Lake Baikal OA Soutourina, EA Semenova, VV Parfenova, A Danchin, P Bertin Applied and Environmental Microbiology 67 (9), 3852-3859, 2001 | 72 | 2001 |