In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase W Nomura, CF Barbas Journal of the American Chemical Society 129 (28), 8676-8677, 2007 | 140 | 2007 |
Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells T Tanaka, W Nomura, T Narumi, A Masuda, H Tamamura Journal of the American Chemical Society 132 (45), 15899-15901, 2010 | 99 | 2010 |
CD4 mimics targeting the mechanism of HIV entry Y Yamada, C Ochiai, K Yoshimura, T Tanaka, N Ohashi, T Narumi, ... Bioorganic & medicinal chemistry letters 20 (1), 354-358, 2010 | 75 | 2010 |
Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products W Nomura, H Aikawa, N Ohashi, E Urano, M Métifiot, M Fujino, K Maddali, ... ACS chemical biology 8 (10), 2235-2244, 2013 | 57 | 2013 |
Fluorophore labeling enables imaging and evaluation of specific cxcr4− ligand interaction at the cell membrane for fluorescence-based screening W Nomura, Y Tanabe, H Tsutsumi, T Tanaka, K Ohba, N Yamamoto, ... Bioconjugate chemistry 19 (9), 1917-1920, 2008 | 54 | 2008 |
CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist T Narumi, C Ochiai, K Yoshimura, S Harada, T Tanaka, W Nomura, H Arai, ... Bioorganic & medicinal chemistry letters 20 (19), 5853-5858, 2010 | 52 | 2010 |
Small molecular CD4 mimics as HIV entry inhibitors T Narumi, H Arai, K Yoshimura, S Harada, W Nomura, S Matsushita, ... Bioorganic & medicinal chemistry 19 (22), 6735-6742, 2011 | 48 | 2011 |
Azamacrocyclic metal complexes as CXCR4 antagonists T Tanaka, T Narumi, T Ozaki, A Sohma, N Ohashi, C Hashimoto, K Itotani, ... ChemMedChem 6 (5), 834-839, 2011 | 47 | 2011 |
Peptide HIV-1 integrase inhibitors from HIV-1 gene products S Suzuki, E Urano, C Hashimoto, H Tsutsumi, T Nakahara, T Tanaka, ... Journal of medicinal chemistry 53 (14), 5356-5360, 2010 | 46 | 2010 |
A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy D Matsumoto, H Tamamura, W Nomura Communications biology 3 (1), 601, 2020 | 45 | 2020 |
Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells H Tsutsumi, W Nomura, S Abe, T Mino, A Masuda, N Ohashi, T Tanaka, ... Angewandte Chemie-International Edition 48 (48), 9164-9166, 2009 | 45 | 2009 |
Corrigendum: A Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase in Inhibition Potency W Nomura, C Hashimoto, A Ohya, K Miyauchi, E Urano, T Tanaka, ... ChemMedChem 7 (4), 546, 2012 | 44 | 2012 |
Small‐Molecule CD4 Mimics Containing Mono‐cyclohexyl Moieties as HIV Entry Inhibitors N Ohashi, S Harada, T Mizuguchi, Y Irahara, Y Yamada, M Kotani, ... ChemMedChem 11 (8), 940-946, 2016 | 39 | 2016 |
CD4 mimics as HIV entry inhibitors: lead optimization studies of the aromatic substituents T Narumi, H Arai, K Yoshimura, S Harada, Y Hirota, N Ohashi, ... Bioorganic & medicinal chemistry 21 (9), 2518-2526, 2013 | 39 | 2013 |
Significant effect of linker sequence on DNA recognition by multi-zinc finger protein M Nagaoka, W Nomura, Y Shiraishi, Y Sugiura Biochemical and Biophysical Research Communications 282 (4), 1001-1007, 2001 | 34 | 2001 |
Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C–induced HIV latency reversal K Matsuda, T Kobayakawa, K Tsuchiya, S Hattori, W Nomura, H Gatanaga, ... Journal of Biological Chemistry 294 (1), 116-129, 2019 | 33 | 2019 |
Multimerized CHR-derived peptides as HIV-1 fusion inhibitors W Nomura, C Hashimoto, T Suzuki, N Ohashi, M Fujino, T Murakami, ... Bioorganic & medicinal chemistry 21 (15), 4452-4458, 2013 | 31 | 2013 |
Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies T Nakahara, W Nomura, K Ohba, A Ohya, T Tanaka, C Hashimoto, ... Bioconjugate chemistry 21 (4), 709-714, 2010 | 31 | 2010 |
A minimally cytotoxic CD4 mimic as an HIV entry inhibitor T Mizuguchi, S Harada, T Miura, N Ohashi, T Narumi, H Mori, Y Irahara, ... Bioorganic & Medicinal Chemistry Letters 26 (2), 397-400, 2016 | 30 | 2016 |
Microwave-Assisted synthesis of azacoumarin fluorophores and the fluorescence characterization H Takano, T Narumi, W Nomura, H Tamamura The Journal of Organic Chemistry 82 (5), 2739-2744, 2017 | 29 | 2017 |