Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis G Bashiri, AM Rehan, DR Greenwood, JMJ Dickson, EN Baker PloS one 5 (12), e15803, 2010 | 152 | 2010 |
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of … G Bashiri, CJ Squire, NJ Moreland, EN Baker Journal of Biological Chemistry 283 (25), 17531-17541, 2008 | 118 | 2008 |
Functional Genome Mining Reveals a Class V Lanthipeptide Containing a d‐Amino Acid Introduced by an F420H2‐Dependent Reductase M Xu, F Zhang, Z Cheng, G Bashiri, J Wang, J Hong, Y Wang, L Xu, ... Angewandte Chemie International Edition 59 (41), 18029-18035, 2020 | 109 | 2020 |
Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis P Wang, G Bashiri, X Gao, MR Sawaya, Y Tang Journal of the American Chemical Society 135 (19), 7138-7141, 2013 | 104 | 2013 |
Mutations in fbiD (Rv2983) as a Novel Determinant of Resistance to Pretomanid and Delamanid in Mycobacterium tuberculosis D Rifat, SY Li, T Ioerger, K Shah, JP Lanoix, J Lee, G Bashiri, J Sacchettini, ... Antimicrobial agents and chemotherapy 65 (1), 10.1128/aac. 01948-20, 2020 | 82 | 2020 |
A new Gateway® vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis RM Goldstone, NJ Moreland, G Bashiri, EN Baker, JS Lott Protein expression and purification 57 (1), 81-87, 2008 | 72 | 2008 |
Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies G Bashiri, EN Baker Protein science 24 (1), 1-10, 2015 | 70 | 2015 |
A revised biosynthetic pathway for the cofactor F420 in prokaryotes G Bashiri, J Antoney, ENM Jirgis, MV Shah, B Ney, J Copp, SM Stuteley, ... Nature communications 10 (1), 1558, 2019 | 68 | 2019 |
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system G Bashiri, CJ Squire, EN Baker, NJ Moreland Protein expression and purification 54 (1), 38-44, 2007 | 66 | 2007 |
Targeting isocitrate lyase for the treatment of latent tuberculosis RP Bhusal, G Bashiri, BXC Kwai, J Sperry, IKH Leung Drug Discovery Today 22 (7), 1008-1016, 2017 | 56 | 2017 |
Itaconate is a covalent inhibitor of the Mycobacterium tuberculosis isocitrate lyase BXC Kwai, AJ Collins, MJ Middleditch, J Sperry, G Bashiri, IKH Leung RSC Medicinal Chemistry 12 (1), 57-61, 2021 | 52 | 2021 |
β-NAD as a building block in natural product biosynthesis L Barra, T Awakawa, K Shirai, Z Hu, G Bashiri, I Abe Nature 600 (7890), 754-758, 2021 | 51 | 2021 |
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography RD Bunker, K Mandal, G Bashiri, JJ Chaston, BL Pentelute, JS Lott, ... Proceedings of the National Academy of Sciences 112 (14), 4310-4315, 2015 | 51 | 2015 |
A NADH-accepting imine reductase variant: immobilization and cofactor regeneration by oxidative deamination M Gand, C Thöle, H Müller, H Brundiek, G Bashiri, M Höhne Journal of biotechnology 230, 11-18, 2016 | 48 | 2016 |
Regulation and quality control of adiponectin assembly by endoplasmic reticulum chaperone ERp44 L Hampe, M Radjainia, C Xu, PWR Harris, G Bashiri, DC Goldstone, ... Journal of Biological Chemistry 290 (29), 18111-18123, 2015 | 44 | 2015 |
Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase H Ichikawa, G Bashiri, WL Kelly Journal of the American Chemical Society 140 (34), 10749-10756, 2018 | 39 | 2018 |
Tat–Dependent Translocation of an F420–Binding Protein of Mycobacterium tuberculosis G Bashiri, EF Perkowski, AP Turner, ME Feltcher, M Braunstein, EN Baker Public Library of Science 7 (10), e45003, 2012 | 38 | 2012 |
Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver M Dogra, BD Palmer, G Bashiri, MD Tingle, SS Shinde, RF Anderson, ... British journal of pharmacology 162 (1), 226-236, 2011 | 33 | 2011 |
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2 RP Bhusal, W Jiao, BXC Kwai, J Reynisson, AJ Collins, J Sperry, ... Nature Communications 10 (1), 4639, 2019 | 31 | 2019 |
Structural views along the Mycobacterium tuberculosis MenD reaction pathway illuminate key aspects of thiamin diphosphate-dependent enzyme mechanisms ENM Jirgis, G Bashiri, EMM Bulloch, JM Johnston, EN Baker Structure 24 (7), 1167-1177, 2016 | 30 | 2016 |