Antibiotics as intermicrobial signaling agents instead of weapons JF Linares, I Gustafsson, F Baquero, JL Martinez Proceedings of the National Academy of Sciences 103 (51), 19484-19489, 2006 | 839 | 2006 |
The signaling adaptor p62 is an important NF-κB mediator in tumorigenesis A Duran, JF Linares, AS Galvez, K Wikenheiser, JM Flores, MT Diaz-Meco, ... Cancer cell 13 (4), 343-354, 2008 | 647 | 2008 |
p62 is a key regulator of nutrient sensing in the mTORC1 pathway A Duran, R Amanchy, JF Linares, J Joshi, S Abu-Baker, A Porollo, ... Molecular cell 44 (1), 134-146, 2011 | 555 | 2011 |
p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 437 | 2016 |
A global view of antibiotic resistance JL Martinez, A Fajardo, L Garmendia, A Hernandez, JF Linares, ... FEMS microbiology reviews 33 (1), 44-65, 2008 | 435 | 2008 |
A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis SR Alonso, L Tracey, P Ortiz, B Pérez-Gómez, J Palacios, M Pollán, ... Cancer research 67 (7), 3450-3460, 2007 | 382 | 2007 |
K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells JF Linares, A Duran, T Yajima, M Pasparakis, J Moscat, MT Diaz-Meco Molecular cell 51 (3), 283-296, 2013 | 266 | 2013 |
Fitness of in vitro selected Pseudomonas aeruginosanalB and nfxB multidrug resistant mutants P Sánchez, JF Linares, B Ruiz-Díez, E Campanario, A Navas, F Baquero, ... Journal of Antimicrobial Chemotherapy 50 (5), 657-664, 2002 | 249 | 2002 |
Overexpression of the Multidrug Efflux Pumps MexCD-OprJ and MexEF-OprN Is Associated with a Reduction of Type III Secretion in Pseudomonas aeruginosa JF Linares, JA López, E Camafeita, JP Albar, F Rojo, JL Martínez Journal of bacteriology 187 (4), 1384-1391, 2005 | 225 | 2005 |
The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa JF Linares, R Moreno, A Fajardo, L Martínez‐Solano, R Escalante, F Rojo, ... Environmental microbiology 12 (12), 3196-3212, 2010 | 183 | 2010 |
Increased serine and one-carbon pathway metabolism by PKCλ/ι deficiency promotes neuroendocrine prostate cancer M Reina-Campos, JF Linares, A Duran, T Cordes, A L'Hermitte, MG Badur, ... Cancer Cell 35 (3), 385-400. e9, 2019 | 171 | 2019 |
The Pseudomonas putida Crc Global Regulator Controls the Expression of Genes from Several Chromosomal Catabolic Pathways for Aromatic Compounds G Morales, JF Linares, A Beloso, JP Albar, JL Martínez, F Rojo Journal of bacteriology 186 (5), 1337-1344, 2004 | 161 | 2004 |
Overproduction of the multidrug efflux pump MexEF‐OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in … J Olivares, C Alvarez‐Ortega, JF Linares, F Rojo, T Köhler, JL Martínez Environmental microbiology 14 (8), 1968-1981, 2012 | 127 | 2012 |
Amino acid activation of mTORC1 by a PB1-domain-driven kinase complex cascade JF Linares, A Duran, M Reina-Campos, P Aza-Blanc, A Campos, J Moscat, ... Cell reports 12 (8), 1339-1352, 2015 | 119 | 2015 |
ATF4-induced metabolic reprograming is a synthetic vulnerability of the p62-deficient tumor stroma JF Linares, T Cordes, A Duran, M Reina-Campos, T Valencia, CS Ahn, ... Cell metabolism 26 (6), 817-829. e6, 2017 | 101 | 2017 |
Protein kinase Cζ represses the interleukin-6 promoter and impairs tumorigenesis in vivo AS Galvez, A Duran, JF Linares, P Pathrose, EA Castilla, S Abu-Baker, ... Molecular and cellular biology, 2009 | 101 | 2009 |
PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression Y Kudo, M Sugimoto, E Arias, H Kasashima, T Cordes, JF Linares, ... Cancer Cell 38 (2), 247-262. e11, 2020 | 98 | 2020 |
Par‐4 inhibits Akt and suppresses Ras‐induced lung tumorigenesis J Joshi, PJ Fernandez‐Marcos, A Galvez, R Amanchy, JF Linares, ... The EMBO journal 27 (16), 2181-2193, 2008 | 98 | 2008 |
Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation JF Linares, R Amanchy, MT Diaz-Meco, J Moscat Molecular and cellular biology 31 (1), 105-117, 2011 | 89 | 2011 |
Repression of intestinal stem cell function and tumorigenesis through direct phosphorylation of β-catenin and Yap by PKCζ V Llado, Y Nakanishi, A Duran, M Reina-Campos, PM Shelton, JF Linares, ... Cell reports 10 (5), 740-754, 2015 | 88 | 2015 |