Clinical development of a poly (2-oxazoline)(POZ) polymer therapeutic for the treatment of Parkinson’s disease–Proof of concept of POZ as a versatile polymer platform for drug … RW Moreadith, TX Viegas, MD Bentley, JM Harris, Z Fang, K Yoon, ... European Polymer Journal 88, 524-552, 2017 | 155 | 2017 |
Improving the serum stability of site-specific antibody conjugates with sulfone linkers JT Patterson, S Asano, X Li, C Rader, CF Barbas III Bioconjugate chemistry 25 (8), 1402-1407, 2014 | 101 | 2014 |
Strain prioritization and genome mining for enediyne natural products X Yan, H Ge, T Huang, Hindra, D Yang, Q Teng, I Crnovčić, X Li, ... MBio 7 (6), 10.1128/mbio. 02104-16, 2016 | 95 | 2016 |
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates AR Nanna, X Li, E Walseng, L Pedzisa, RS Goydel, D Hymel, TR Burke Jr, ... Nature communications 8 (1), 1112, 2017 | 82 | 2017 |
Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1 J Qi, X Li, H Peng, EM Cook, EL Dadashian, A Wiestner, HJ Park, ... Proceedings of the National Academy of Sciences 115 (24), E5467-E5476, 2018 | 72 | 2018 |
Activation of Thromboxane A2 Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2 … X Li, HH Tai PloS one 8 (1), e54073, 2013 | 71 | 2013 |
Activation of thromboxane A 2 receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells X Li, HH Tai Carcinogenesis 30 (9), 1606-1613, 2009 | 67 | 2009 |
Site-specific dual antibody conjugation via engineered cysteine and selenocysteine residues X Li, JT Patterson, M Sarkar, L Pedzisa, T Kodadek, WR Roush, C Rader Bioconjugate chemistry 26 (11), 2243-2248, 2015 | 63 | 2015 |
Thromboxane receptor α mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells J Wei, W Yan, X Li, Y Ding, HH Tai Lung cancer 69 (1), 26-32, 2010 | 57 | 2010 |
Antibody conjugation via one and two C-terminal selenocysteines X Li, J Yang, C Rader Methods 65 (1), 133-138, 2014 | 54 | 2014 |
Dual-mechanistic antibody-drug conjugate via site-specific selenocysteine/cysteine conjugation N Nilchan, X Li, L Pedzisa, AR Nanna, WR Roush, C Rader Antibody therapeutics 2 (4), 71-78, 2019 | 51 | 2019 |
Mining naive rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility H Peng, T Nerreter, J Chang, J Qi, X Li, P Karunadharma, GJ Martinez, ... Journal of molecular biology 429 (19), 2954-2973, 2017 | 51 | 2017 |
Stable and potent selenomab-drug conjugates X Li, CG Nelson, RR Nair, L Hazlehurst, T Moroni, P Martinez-Acedo, ... Cell chemical biology 24 (4), 433-442. e6, 2017 | 45 | 2017 |
Thromboxane A2 receptor‐mediated release of matrix metalloproteinase‐1 (MMP‐1) induces expression of monocyte chemoattractant protein‐1 (MCP‐1) by … X Li, HH Tai Molecular carcinogenesis 53 (8), 659-666, 2014 | 43 | 2014 |
Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion M Ma, ME Rateb, Q Teng, D Yang, JD Rudolf, X Zhu, Y Huang, LX Zhao, ... Journal of natural products 78 (10), 2471-2480, 2015 | 40 | 2015 |
Activation of thromboxane receptor α induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells J Wei, W Yan, X Li, WC Chang, HH Tai Biochemical pharmacology 74 (5), 787-800, 2007 | 34 | 2007 |
Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts L Pedzisa, X Li, C Rader, WR Roush Organic & biomolecular chemistry 14 (22), 5141-5147, 2016 | 24 | 2016 |
Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells X Li, HH Tai Current cancer drug targets 12 (6), 703-715, 2012 | 21 | 2012 |
Tagging the untaggable: A difluoroalkyl-sulfinate ketone-based reagent for direct C–H functionalization of bioactive heteroarenes S Gnaim, A Scomparin, X Li, PS Baran, C Rader, R Satchi-Fainaro, ... Bioconjugate Chemistry 27 (9), 1965-1971, 2016 | 16 | 2016 |
高纯度血红素制备工艺的改进 李秀玲, 余蓉, 杨继虞, 曾蓉 四川大学学报: 医学版 35 (5), 738-738, 2004 | 15 | 2004 |