Positive epistasis drives the acquisition of multidrug resistance S Trindade, A Sousa, KB Xavier, F Dionisio, MG Ferreira, I Gordo PLoS genetics 5 (7), e1000578, 2009 | 304 | 2009 |
The First Steps of Adaptation of Escherichia coli to the Gut Are Dominated by Soft Sweeps J Barroso-Batista, A Sousa, M Lourenço, ML Bergman, D Sobral, ... PLoS genetics 10 (3), e1004182, 2014 | 189 | 2014 |
Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut N Frazão, A Sousa, M Lässig, I Gordo Proceedings of the National Academy of Sciences 116 (36), 17906-17915, 2019 | 154 | 2019 |
Rates of fitness decline and rebound suggest pervasive epistasis L Perfeito, A Sousa, T Bataillon, I Gordo Evolution 68 (1), 150-162, 2014 | 104 | 2014 |
Cost of antibiotic resistance and the geometry of adaptation A Sousa, S Magalhaes, I Gordo Molecular biology and evolution 29 (5), 1417-1428, 2012 | 95 | 2012 |
The Genetic Basis of Escherichia coli Pathoadaptation to Macrophages M Miskinyte, A Sousa, RS Ramiro, JAM de Sousa, J Kotlinowski, ... PLoS pathogens 9 (12), e1003802, 2013 | 90 | 2013 |
Antibiotic resistance and stress in the light of Fisher's model S Trindade, A Sousa, I Gordo Evolution 66 (12), 3815-3824, 2012 | 81 | 2012 |
Rates of transposition in Escherichia coli A Sousa, C Bourgard, LM Wahl, I Gordo Biology letters 9 (6), 20130838, 2013 | 77 | 2013 |
Fitness effects of mutations in bacteria I Gordo, L Perfeito, A Sousa Journal of molecular microbiology and biotechnology 21 (1-2), 20-35, 2012 | 67 | 2012 |
Multiple resistance at no cost: rifampicin and streptomycin a dangerous liaison in the spread of antibiotic resistance P Durão, S Trindade, A Sousa, I Gordo Molecular biology and evolution 32 (10), 2675-2680, 2015 | 57 | 2015 |
The landscape of adaptive evolution of a gut commensal bacteria in aging mice HC Barreto, A Sousa, I Gordo Current Biology 30 (6), 1102-1109. e5, 2020 | 49 | 2020 |
A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut AS Marta Lourenço, Ricardo S. Ramiro, Daniela Guleresi, João Barroso-Batista ... PLOS Genetics, 2016 | 44 | 2016 |
Recurrent Reverse Evolution Maintains Polymorphism after Strong Bottlenecks in Commensal Gut Bacteria A Sousa, R S. Ramiro, J Barroso-Batista, D Gu¨leresi, ... Molecular Biology and Evolution, 2017 | 43 | 2017 |
Evolution of commensal bacteria in the intestinal tract of mice A Sousa, N Frazão, R S. Ramiro, I Gordo Current Opinion in Microbiology 38, 114-121, 2017 | 38 | 2017 |
rRNA Intergenic Spacer Regions for Phylogenetic Analysis of Rickettsia Species L Vitorino, L ZÉ‐ZÉ, A Sousa, F Bacellar, R Tenreiro Annals of the New york Academy of Sciences 990 (1), 726-733, 2003 | 36 | 2003 |
Potential for adaptation overrides cost of resistance J Moura de Sousa, A Sousa, C Bourgard, I Gordo Future microbiology 10 (9), 1415-1431, 2015 | 19 | 2015 |
Trade-Offs of Escherichia coli Adaptation to an Intracellular Lifestyle in Macrophages M Azevedo, A Sousa, J Moura de Sousa, JA Thompson, JT Proença, ... PLoS One 11 (1), e0146123, 2016 | 17 | 2016 |
The Selective Advantage of the lac Operon for Escherichia coli Is Conditional on Diet and Microbiota Composition C Pinto, R Melo-Miranda, I Gordo, A Sousa Frontiers in microbiology 12, 709259, 2021 | 15 | 2021 |
Mutation accumulation and horizontal gene transfer in Escherichia coli colonizing the gut of old mice GI Barreto HC, Frazão N, SOUSA, A, Konrad A Communicative & Integrative Biology, 2020 | 14 | 2020 |
Saliva as a non-invasive specimen for COPD assessment S Melo-Dias, C Valente, L Andrade, A Marques, A Sousa Respiratory research 23 (1), 16, 2022 | 13 | 2022 |