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Francine E. Garrett-Bakelman
Francine E. Garrett-Bakelman
Assistant Professor of Medicine and Biochemistry and Molecular Genetics, University of Virginia
Verified email at virginia.edu - Homepage
Title
Cited by
Cited by
Year
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ...
Genome biology 13, 1-9, 2012
19222012
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ...
Nature medicine 23 (11), 1369-1376, 2017
11042017
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ...
Science 364 (6436), eaau8650, 2019
9782019
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia
S Li, FE Garrett-Bakelman, SS Chung, MA Sanders, T Hricik, F Rapaport, ...
Nature medicine 22 (7), 792-799, 2016
4022016
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
A Akalin, FE Garrett-Bakelman, M Kormaksson, J Busuttil, L Zhang, ...
PLoS genetics 8 (6), e1002781, 2012
3392012
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling
OA Guryanova, K Shank, B Spitzer, L Luciani, RP Koche, ...
Nature medicine 22 (12), 1488-1495, 2016
2622016
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013
1952013
Chemotherapy induces senescence-like resilient cells capable of initiating AML recurrence
C Duy, M Li, M Teater, C Meydan, FE Garrett-Bakelman, TC Lee, CR Chin, ...
Cancer discovery 11 (6), 1542-1561, 2021
1912021
Chromatin Architecture near a Potential 3′ End of the Igh Locus Involves Modular Regulation of Histone Modifications during B-Cell Development and In Vivo …
FE Garrett, AV Emelyanov, MA Sepulveda, P Flanagan, S Volpi, F Li, ...
Molecular and cellular biology 25 (4), 1511-1525, 2005
1492005
CD99 is a therapeutic target on disease stem cells in myeloid malignancies
SS Chung, WS Eng, W Hu, M Khalaj, FE Garrett-Bakelman, M Tavakkoli, ...
Science translational medicine 9 (374), eaaj2025, 2017
1472017
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia
AH Shih, C Meydan, K Shank, FE Garrett-Bakelman, PS Ward, ...
Cancer discovery 7 (5), 494-505, 2017
1262017
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution
FE Garrett-Bakelman, CK Sheridan, TJ Kacmarczyk, J Ishii, D Betel, ...
Journal of visualized experiments: JoVE, 52246, 2015
1262015
Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers
JL Glass, D Hassane, BJ Wouters, H Kunimoto, R Avellino, ...
Cancer discovery 7 (8), 868-883, 2017
1242017
An optimized algorithm for detecting and annotating regional differential methylation
S Li, FE Garrett-Bakelman, A Akalin, P Zumbo, R Levine, BL To, ID Lewis, ...
BMC bioinformatics 14, 1-9, 2013
1222013
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment
B Will, TO Vogler, B Bartholdy, F Garrett-Bakelman, J Mayer, L Barreyro, ...
Nature immunology 14 (5), 437-445, 2013
1192013
Cooperative epigenetic remodeling by TET2 loss and NRAS mutation drives myeloid transformation and MEK inhibitor sensitivity
H Kunimoto, C Meydan, A Nazir, J Whitfield, K Shank, F Rapaport, ...
Cancer cell 33 (1), 44-59. e8, 2018
952018
Dynamic evolution of clonal epialleles revealed by methclone
S Li, F Garrett-Bakelman, AE Perl, SM Luger, C Zhang, BL To, ID Lewis, ...
Genome biology 15, 1-12, 2014
862014
Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells
OA Guryanova, YK Lieu, FE Garrett-Bakelman, B Spitzer, JL Glass, ...
Leukemia 30 (5), 1133-1142, 2016
782016
Temporal telomere and DNA damage responses in the space radiation environment
JJ Luxton, MJ McKenna, LE Taylor, KA George, SR Zwart, BE Crucian, ...
Cell Reports 33 (10), 2020
712020
The effects of Eculizumab on the pathology of malignant atrophic papulosis
CM Magro, X Wang, F Garrett-Bakelman, J Laurence, LS Shapiro, ...
Orphanet Journal of Rare Diseases 8, 1-9, 2013
662013
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